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Dr. Frank P. Primiano, Jr.,
Vice President, Director of Biomedical Research
Education: Baldwin Wallace College, Cleveland, OH
MBA 1989
Case Western Reserve University, Cleveland OH
Ph.D. in Biomedical Engineering, 1971
Drexel University, Philadelphia, PA
M.S. in Biomedical Engineering, 1963
B.S. in Mechanical Engineering, 1962
Dr. Frank P. Primiano, Jr.'s work in biomedical modeling and research includes the determination of mechanical properties of arteries in vivo, the breathing response of the ventilatory system to changes in mechanical properties, the investigation of response to conventional and high-frequency ventilation, and the development and automated analysis of pulmonary function testing procedures. During his professional career, he has been a Professor at Case Western Reserve University, a principal member of a company involved with repairing respiratory equipment, and a senior scientist at ECRI. Dr. Primiano has published extensively and continues to lead and participate in professional committees in the respiratory care community.

He has extensive clinical experience in designing and implementing experiments on normal subjects, patients with various pulmonary diseases (such as cystic fibrosis and emphysema), and animal models. Recently, he has actively participated in the development of computer implementations of ventilation, including 3-D visualization. Dr. Primiano has developed various models demonstrating the mechanisms of respiration, such as the humidification process in the upper airways and the ventilatory mechanics of the chest wall and lungs, including the model being used as a basis for this research.

Selected Publications

  • Primiano FP Jr. Chapter 9: Measurements of the respiratory system. In: Webster JG, ed. Medical instrumentation, application and design. 3rd ed. New York: John Wiley & Sons, 1998:372-439.

  • Minimum requirements for respiratory care ventilator testing. Health Devices 1997 Sept - Oct; 26(9-10): 383-384.

  • Radiographic contrast media conservation systems. Health Devices; 1996 Nov; 25(11):400-412.

  • Primiano FP Jr, Saidel GM, Montague FW Jr, et al. Water vapour and temperature dynamics in the upper airways of normal and CF subjects. Eur Respir J 1988; 1:407-14.

  • Chatburn RL, Primiano FP Jr. A rational basis for humidity therapy. Respir Care 1987; 32(4):249-54.

  • Primiano FP Jr. Theoretical analysis of chest wall mechanics. J Biomech 1982; 15(12):919-31.

  • Margolith A, Primiano FP Jr, Mergler HW. Computational algorithms used in a microcomputer-based blood gas analyzer. In: Moneta J, ed. Information technology. (Proceedings of the 3rd Annual Jerusalem Conference on Information Technology [JCIT 3]). Amsterdam: North Holland Publishing Company, 1978:381-6.

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